Health conditions, immune dysfunction, and premature aging associated with trisomy 21 (Down syndrome, DS) may impact the clinical course of COVID-19. </iframe Source: Anke Huls et al. Tags:Alzheimer's Diseaseantibody responsesb-cellsco-occurring health conditionscomorbid conditionscongenital heart defectsCoronavirusCOVIDCovid-19cytokine stormdiabetesgastroesophageal refluxhealth careHealth care professionalshealthcarehealthcare professionalshypotoniaimmune dysfunctionmedical complicationsmortalityobesityobstructive sleep apneaOSApandemicpneumoniapractitionerspremature agingresearchrespiratory tract infectionrisk factorssars-cov2symptomst-cellsT21RS