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Key Points 

  • How the body manages (regulates) body temperature is different in people with Down syndrome compared to people without Down syndrome.
  • The difference in body temperature regulation in people with Down syndrome may be due to multiple factors including differences in blood flow to the skin, sweating, and, in some individuals, abnormal thyroid function.
  • This difference may have implications for when a person with Down syndrome is exposed to hot or cold conditions or has an infection.

Source: Brian Chicoine, MD – Medical Director, Adult Down Syndrome Center