cognitive decline

Resources for Professionals

Diagnosis and treatment of late-onset myoclonic epilepsy in Down syndrome (LOMEDS): A systematic review with individual patients’ data analysis

The late onset myoclonic epilepsy in Down Syndrome (LOMEDS) is a peculiar epilepsy type characterized…

Kim WarrenMarch 28, 2024

Resources for Professionals

Adapting Eligibility Criteria for Prescribing FDA Approved Anti-amyloid Immunotherapeutics for Adults with Down Syndrome with Early-Stage Alzheimer’s Dementia

An international group of experts convened to determine prescribing criteria equivalences that would be inclusionary…

Kim WarrenJune 2, 2023

Resources for Professionals

Mechanistic Analysis of Age-Related Clinical Manifestations in Down Syndrome

Studies suggest human trisomy 21 impacts several diseases in an age-dependent manner. Thus, understanding the…

Rigsby RigsbyApril 29, 2022

Resources for Professionals

Down Syndrome Disintegrative Disorder: A Clinical Regression Syndrome of Increasing Importance

Down syndrome disintegrative disorder (DSDD), a developmental regression in children with Down syndrome (DS), is…

Rigsby RigsbyApril 16, 2022

Resources for Professionals

Down Syndrome: Review Article

Down syndrome, also called Down’s syndrome (DS), is the most common chromosomal condition associated with…

Rigsby RigsbyApril 6, 2022

Resources for Professionals

Clinical Aspects and Biomarkers of Alzheimer’s Disease in Down Syndrome

Alzheimer's disease (AD) may affect in excess of 90% of individuals with Down syndrome (DS)…

Rigsby RigsbyApril 5, 2022

Ask Dr. Brian Chicoine Health and Research – Other

Psychoses, Depression, Behavioral Changes, Family Support, Medications

Question: My 57-year-old brother has hallucinations and delusions. What can be done for this? He's…

Capetivate capetivateAugust 12, 2021

Health and Research – Other

Effect of Menopause on Cognition in Women with Down Syndrome?

What is the effect of menopause on cognition in women with Down syndrome? Menopause, defined…

Capetivate capetivateJuly 12, 2021

Ask Dr. Brian Chicoine Health and Research – Other

Intravenous Immunoglobulin

Question: My question is about Neuropsychological issues. My daughter's began quite suddenly when she was…

Capetivate capetivateMarch 18, 2021

Ask Dr. Brian Chicoine Health and Research – Other

Loss of Skills

Question: My 46-year-old son was diagnosed with Alzheimer’s disease more than 5 years ago. I’m…

Capetivate capetivateOctober 4, 2020

cognitive decline

Diagnosis and treatment of late-onset myoclonic epilepsy in Down syndrome (LOMEDS): A systematic review with individual patients’ data analysis

Adapting Eligibility Criteria for Prescribing FDA Approved Anti-amyloid Immunotherapeutics for Adults with Down Syndrome with Early-Stage Alzheimer’s Dementia

Mechanistic Analysis of Age-Related Clinical Manifestations in Down Syndrome

Clinical Aspects and Biomarkers of Alzheimer’s Disease in Down Syndrome

Psychoses, Depression, Behavioral Changes, Family Support, Medications

Effect of Menopause on Cognition in Women with Down Syndrome?

Intravenous Immunoglobulin

Loss of Skills

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