We were sent a question about Down syndrome and Wolff-Parkinson-White (WPW) syndrome and Bicuspid Aortic Valve. WPW is a heart condition in which there is an extra electrical pathway in the heart. Source: Brian Chicoine, MD Tags:Bicuspid Aortic ValvecardiologyCongenital Heart DefecthealthHealthy livingheart defectheart defectshearth healthWolff-Parkinson-White SyndromeWPW